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research Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes

3 citations , February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY”

Certain genes are linked to skin aging, like wrinkles and pigmentation changes.

research Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development

22 citations , August 1999 in “Mechanisms of Development”

Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.

research Using WGCNA (weighted gene co-expression network analysis) to identify the hub genes of skin hair follicle development in fetus stage of Inner Mongolia cashmere goat

16 citations , December 2020 in “PloS one”

Researchers found WNT10A to be a key gene in developing goat hair follicles.

research Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination

2 citations , April 2025 in “Frontiers in Genetics”

The ASIP gene is crucial for determining cattle coat color.

research Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction

87 citations , July 2009 in “Journal of Cell Science”

Deleting the CDSN gene causes severe skin and hair problems, leading to death.

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community Is it possible to transplant mice skin into human body?

in Transplants 47 upvotes 8 months ago

Transplanting mice skin to humans is not feasible due to immune rejection, but some suggest genetic modification or immune suppression could make it possible. Xenograft hair transplants are discouraged.

community Has anyone had positive experiences with Dutasteride?

in Finasteride/Dutasteride 21 upvotes 2 years ago

Dutasteride is generally considered more effective than finasteride for hair regrowth and thickening, despite some negative anecdotal reports. Users report thicker hair and better skin with dutasteride, and some believe negative reviews are due to advanced alopecia or impatience with the shedding process.

community Welcome to Tressless, OG! Ötzi was dark-skinned and balding.

in Chat 11 upvotes 2 years ago

The conversation discusses that genetic analysis of the Iceman Ötzi shows he had male-pattern baldness and dark skin, with a joke about using beards and tattoos to distract from hair loss. No specific hair loss treatments are mentioned.

community 29f Female on Dutasteride Progress.

in Female 14 upvotes 2 years ago

A 29-year-old woman with genetic hair loss started using 0.5 dutasteride a week ago and has noticed increased shedding, no sexual side effects, and less oily skin. She plans to provide updates and is not concerned about potential birth defects as she doesn't plan to have more children.

community Very high testosterone and estradiol on finasterid 1 mg. Am I cooked?

in Finasteride/Dutasteride 3 upvotes 7 months ago

A 29-year-old male on 1 mg Finasteride for 3 months has experienced a significant increase in testosterone and estradiol levels, with no major side effects except slightly oilier skin and increased emotional sensitivity. The user is concerned about these hormonal changes and seeks advice, as their general practitioner is not knowledgeable about the issue.

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