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GlossaryBasal Cell Carcinoma

most common skin cancer, originating in basal epidermal cells

Basal Cell Carcinoma (BCC) is the most common type of skin cancer, originating in the basal cells, which are found in the deepest layer of the epidermis. It typically appears as a small, shiny bump or nodule on sun-exposed areas of the skin, such as the face and neck, and is usually caused by long-term exposure to ultraviolet (UV) radiation from the sun or tanning beds. While BCC rarely metastasizes, it can cause significant local damage if not treated promptly.

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Research

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research Identical p53 gene mutation in malignant proliferating trichilemmal tumour of the scalp and small cell carcinoma of the common bile duct: the necessity for therapeutic caution?

11 citations , May 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

Identical p53 gene mutations in different cancers suggest the need for careful treatment.

Novel Small Molecules Downregulate CDK1 Expression and Inhibit Wnt/β-Catenin Signaling in Cutaneous Squamous Cell Carcinoma by Targeting Its Distinct Tumor-Specific Cellular Landscape

research Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape

September 2025 in “Experimental & Molecular Medicine”

Small molecules KY19382 and KY19334 may help treat skin cancer by reducing CDK1 levels and blocking harmful cell signals.

research Cytokeratin expression in trichoblastic fibroma (small nodular type trichoblastoma), trichoepithelioma and basal cell carcinoma

87 citations , January 1999 in “British Journal of Dermatology”

Trichoblastic fibroma and basal cell carcinoma are similar but different from trichoepithelioma.

research Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies

45 citations , January 2022 in “Lab on a Chip”

The platform effectively grows lung cancer cell spheroids for drug testing.

research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened

63 citations , May 2011 in “Clinical cancer research”

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

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Community Join

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community Am I wasting my time with this? Need advice

in Is this regrowth? 37 upvotes 11 months ago

The user has been using a combination of finasteride and minoxidil for 5 months and is considering adding dutasteride due to slow progress. They plan to alternate between oral finasteride and dutasteride to save costs and are advised to continue the treatment for more time, possibly adding tretinoin, while considering a hair transplant if results remain unsatisfactory.

community Just found a little hard lump under my left nipple, it’s over

in Finasteride/Dutasteride 12 upvotes 2 years ago

A user experienced a hard lump under their nipple and increased hair loss after four months of finasteride. They are concerned about the lump and plan to stop the treatment.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Anything you use without scientific backing, just trusting your gut?

in Research/Science 13 upvotes 3 years ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community PP405 Drug in Action: Picture From Official Company Website

in Technology 776 upvotes 1 year ago

PP405 shows promise for hair follicle reactivation with minimal side effects. Users recommend continuing Minoxidil and Finasteride until more results are confirmed.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Stem Cell Factor

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

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Small Face Cut & Hair Growth Specialty Salon GoyururiFukuyama · JP

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