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technique to create small wounds in skin to activate collagen production and hair growth
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5 / 10 resultslearn Mesotherapy
technique to inject very small amounts of beneficial chemicals into the scalp
learn Exosomes
Microscopic delivery system that sends growth-promoting signals to hair follicles
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Saw Palmetto
a natural and far less effective alternative to Finasteride
Research
5 / 1000+ resultsresearch A SIBO-Mediated Etiology for a Subset of Post-Finasteride Syndrome Cases: Investigating Gut-Derived Toxins
This theoretical paper suggests a novel gut-centric cause for a subset of Post-Finasteride Syndrome (PFS) cases, which are not fully explained by androgen deprivation. It hypothesizes that a chronic overgrowth of hydrogen sulphide (H₂S)-producing bacteria in the small intestine acts as a systemic mitochondrial toxin. This condition may create a dysbiotic feedback loop that perpetuates the epigenetic silencing initially triggered by finasteride exposure. The paper proposes that this acquired metabolic dysfunction, driven by gut-derived toxins, could explain the persistence of PFS symptoms and highlights the small intestinal microbiome as a potential therapeutic target.
research A SIBO-Mediated Etiology for a Subset of Post-Finasteride Syndrome Cases: Investigating Gut-Derived Toxins
This theoretical paper suggests a novel gut-centric cause for a subset of Post-Finasteride Syndrome (PFS) cases, which are not fully explained by androgen deprivation. It hypothesizes that a chronic overgrowth of hydrogen sulphide (H₂S)-producing bacteria in the small intestine acts as a systemic mitochondrial toxin. This condition may create a dysbiotic feedback loop that perpetuates the epigenetic silencing initially triggered by finasteride exposure. The paper proposes that this acquired metabolic dysfunction, driven by gut-derived toxins, could explain the persistence of PFS symptoms and highlights the small intestinal microbiome as a potential therapeutic target.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research A Complete Guide to Human Microbiomes: Body Niches, Transmission, Development, Dysbiosis, and Restoration
Modern lifestyles harm beneficial microbes, affecting health.
research Celiac Disease: Beyond Diet And Food Awareness
Celiac disease requires more than just a gluten-free diet for effective management.
Community Join
5 / 1000+ resultscommunity Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism
Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.
community The link between hair loss and gut health
The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.
community How is dht not beneficial to you?
DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.
community A Theory on Why Microneedling Works
Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.
community Why can’t we just do another creatine study?
Creatine may worsen hair loss in some, especially with androgenic alopecia, but evidence is mixed. Some users experience no hair loss when using creatine with minoxidil and finasteride, while others notice increased shedding.