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research Testosterone enhances expression and functional activity of epithelial sodium channel (ENaC), cystic fibrosis transmembrane regulator (CFTR) and sodium hydrogen exchanger (NHE) in vas deferens of sex-steroid deficient male rats

6 citations , July 2018 in “Steroids”

Testosterone changes how certain channels work in male rat reproductive tracts, affecting fertility-related fluid balance.

research Sodium Metabisulfite: Effects on Ionic Currents and Excitotoxicity

13 citations , November 2017 in “Neurotoxicity research/Neurotoxicity resarch”

Sodium metabisulfite increases sodium channel activity, leading to higher cell excitability and potential damage.

research Investigating the mechanisms underlying effects of testosterone on blood pressure in normotensive and hypertensive rats / Loh Su Yi

January 2017

Testosterone raises blood pressure by affecting kidney function and brain gene regulation over time.

research Sub-chronic testosterone treatment increases the levels of epithelial sodium channel (ENaC)-α,βandγin the kidney of orchidectomized adult male Sprague–Dawley rats

18 citations , June 2016 in “PeerJ”

Testosterone increases certain kidney protein levels, potentially raising blood pressure.

A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

research A Study of the Expression of Small Conductance Calcium-Activated Potassium Channels (SK1-3) in Sensory Endings of Muscle Spindles and Lanceolate Endings of Hair Follicles in the Rat

17 citations , September 2014 in “PLoS ONE”

SK2 channels help control sensory signals in rat muscle spindles and hair follicles.

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community Novel Formulation To Put An End To Hair Loss Once And For All.

in Research/Science 118 upvotes 9 months ago

A pharmacy student proposed a hair loss treatment using minoxidil, finasteride, clascoterone, and tretinoin, aiming for high effectiveness with minimal side effects. Reactions were mixed, with some questioning its feasibility and others showing interest.

community The Fear of Oral Minoxidil is Overblown

in Research/Science 272 upvotes 1 year ago

Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 51 upvotes 1 year ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

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