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research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior

32 citations , September 2018 in “Journal of pharmaceutical sciences”

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes

research Geranyl Acetate Attenuates Para-phenylenediamine-induced Cytotoxicity, DNA Damage, Apoptosis, and Inflammation in HaCaT Keratinocytes

1 citations , October 2025 in “Iranian journal of pharmaceutical research”

Geranyl acetate can protect skin cells from damage and inflammation caused by para-phenylenediamine.

research Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals

39 citations , November 2016 in “Pharmaceutics”

The hair follicle pathway significantly affects how easily water-loving chemicals pass through the skin.

Intestinal Permeability Study of Minoxidil: Assessment of Minoxidil as a High Permeability Reference Drug for Biopharmaceutics Classification

research Intestinal Permeability Study of Minoxidil: Assessment of Minoxidil as a High Permeability Reference Drug for Biopharmaceutics Classification

13 citations , January 2015 in “Molecular Pharmaceutics”

Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.

research Potassium channel openers: pharmacological and clinical aspects

119 citations , October 1992 in “Fundamental & Clinical Pharmacology”

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

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community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)

in Research 598 upvotes 1 year ago

A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.

community Andrew Schulz stated he had been using a ‘’hair pill’’ for 15 years and it may have caused him infertility

in Satire 134 upvotes 2 years ago

The conversation discusses the potential link between hair loss treatment pills, specifically finasteride, and infertility. Users share their experiences and opinions, with some suggesting that finasteride can temporarily lower sperm count, while others argue that other factors like age and lifestyle could also contribute to infertility.

community 2020 is here, what’s the current state for “upcoming” treatments?

in Technology 75 upvotes 6 years ago

Minoxidil and finasteride are the main treatments for hair loss, with Breezula and hair cloning being explored. No definitive cure is available yet.

community For what it's worth, I just want to state that I also think that adding Dutasteride to Finasteride has made my hair worse

in Finasteride/Dutasteride 19 upvotes 5 years ago

A user shared that adding Dutasteride to Finasteride worsened their hair loss, despite initial improvements with Finasteride alone. Others in the conversation debated the effectiveness of Dutasteride, with some suggesting individual responses vary and others defending its proven efficacy for hair loss.

community Dutasteride half life - conflicting information

in Finasteride/Dutasteride 10 upvotes 2 years ago

The half-life of Dutasteride is commonly stated as around 5 weeks, but some sources suggest it is 170 hours for men aged 20–49, with further information indicating it varies from 3 days to 5 weeks depending on the dose. The user is seeking clarity on these conflicting figures.

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