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research Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche

133 citations , September 2013 in “Nature Reviews Molecular Cell Biology”

Different types of stem cells and their environments are key to skin repair and maintenance.

research Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury

91 citations , December 2010 in “Stem Cells”

Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.

research Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

6 citations , October 2020 in “Frontiers in cell and developmental biology”

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

research ASH2L mediates epidermal differentiation and hair follicle morphogenesis via H3K4me3 modification

April 2024 in “The journal of investigative dermatology/Journal of investigative dermatology”

ASH2L is essential for skin and hair development.

research Dormancy in the stem cell niche

29 citations , March 2012 in “Stem Cell Research & Therapy”

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

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Learn

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learn Hair Multiplication

extract, clone, and reinsert your own hair cells

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Community Join

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community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 677 upvotes 1 year ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community A Theory on Why Microneedling Works

172 upvotes 6 years ago

Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

community PP405 Won’t Work: Follicle Is Miniaturized, Fibrosed, And Missing Key Support Cells

in Research/Science 5 months ago

PP405 is ineffective for miniaturized, fibrosed hair follicles in androgenetic alopecia. AMP303 may activate hair follicle stem cells, but minoxidil and finasteride are still the main treatments.

community Hair theory Scar tissue and Verteporfin

in Chat 25 upvotes 2 years ago

A user suggests that deeper microneedling with Verteporfin injections might help regrow hair in areas with scar tissue, alongside a DHT blocker. Another user explains that hair loss might be due to reduced Wnt/β-Catenin signaling and suggests that treatments like Minoxidil, Finasteride, and microneedling could potentially reverse it.

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