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research Chemical Structure, Classification and Clinical Significance of Steroid Hormones: A Review Article

August 2025 in “Al-Salam Journal for Medical Science”

Steroid hormones are vital for body functions and disease management.

research Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism

July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

research Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride

30 citations , October 2020 in “Nature Communications”

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

research Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride

4 citations , July 2020 in “Research Square (Research Square)”

The research helps understand how finasteride works and aids drug development.

research In silico structural prediction of human steroid 5α-reductase type II

3 citations , March 2016 in “Medicinal Chemistry Research”

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

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Community Join

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community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 3 years ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community Women complaining of bad effects from Winlevi (Clascoterone 1%)

in Treatment 11 upvotes 7 months ago

Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

community Tristan Tate stopped using fin i guess???

in Satire 468 upvotes 1 year ago

Tristan Tate's hair loss is discussed, with mentions of finasteride, minoxidil, and dutasteride as treatments. Users speculate on his hair styling, steroid use, and legal troubles.

community Do hair follicles dies or are dormant ?

in Finasteride/Dutasteride 92 upvotes 1 year ago

Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

community DUPA, Non Responders and Connective Tissue Disorders

in Research/Science 9 upvotes 1 year ago

A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

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