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Immunohistochemical, Pharmacovigilance, and Omics Analyses Reveal the Involvement of ATP-Sensitive K+ Channel Subunits in Cancers: Role in Drug-Disease Interactions

research Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug–disease interactions

3 citations , April 2023 in “Frontiers in Pharmacology”

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

research K _ATP Channels and Cardiovascular Disease

144 citations , March 2013 in “Circulation Research”

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Characterization of Minoxidil/Hydroxypropyl-β-Cyclodextrin Inclusion Complex in Aqueous Alginate Gel Useful for Alopecia Management: Efficacy Evaluation in Male Rats

research Characterization of minoxidil/hydroxypropyl-β-cyclodextrin inclusion complex in aqueous alginate gel useful for alopecia management: Efficacy evaluation in male rat

19 citations , October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics”

The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.

Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrest Growth of Gynecologic Cancers

research Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrests Growth of Gynecologic Cancers

16 citations , May 2020 in “Frontiers in pharmacology”

Minoxidil can stop the growth of ovarian cancer cells without harming the heart.

Skin and Hair Abnormalities of Cantu Syndrome: A Congenital Hypertrichosis Due to a Genetic Alteration Mimicking the Pharmacological Effect of Minoxidil

research Skin and hair abnormalities of Cantu syndrome: A congenital hypertrichosis due to a genetic alteration mimicking the pharmacological effect of minoxidil

7 citations , January 2020 in “Journal of Dermatology”

Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.

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community Creatine is the opposite of minoxidil !

in Research/Science 321 upvotes 9 months ago

Creatine may counteract minoxidil's hair growth effects by closing potassium ATP channels, potentially leading to hair loss in predisposed individuals. Despite anecdotal reports, there is no conclusive evidence linking creatine to hair loss.

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