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research Dermatologic Side Effects of Systemic Targeted Anticancer Therapy

January 2018 in “Springer eBooks”

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

research Clascoterone: a new topical antiandrogen agent.

February 2025 in “Prospects in Pharmaceutical Sciences”

Clascoterone is a promising topical treatment for hair loss and acne with fewer side effects.

research Topical Antiandrogens

11 citations , January 1985 in “Archives of Dermatology”

Topical antiandrogens might treat skin issues like hair growth, balding, and acne, but finding effective treatments without side effects is challenging.

research Management of acne

78 citations , February 2011 in “Canadian Medical Association Journal”

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

research Acne and Systemic Disease

76 citations , November 2009 in “Medical Clinics of North America”

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

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community Which is safest carrier for topical antiandrogens (finasteride/kx-826/ru/dutasteride)

in Finasteride/Dutasteride 6 upvotes 7 months ago

The conversation is about finding a safe carrier for topical antiandrogens like finasteride, kx-826, RU58841, and dutasteride to minimize systemic absorption and side effects. The user experiences side effects from these treatments and is seeking advice on carriers that reduce these effects.

community Keto shampoo and its impact on dht levels?

in Progress Pictures 5 upvotes 1 year ago

Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is considered a mild topical antiandrogen. Users discuss its use for scalp health rather than DHT reduction, with some preferring alternatives like dutasteride over finasteride due to perceived side effects.

community Does ketoconazole reduce systemic DHT by much?

in Treatment 6 upvotes 1 year ago

Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 3 years ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community Hypothetically, if estradiol has been a "cure" for hair loss, could one apply estradiol topically and just take an estrogen blocker and/or testosterone to offset the systematic effects?

in Research/Science 7 upvotes 1 year ago

Topical estradiol may help with hair loss but can have systemic effects, like reduced testosterone production. Using estrogen blockers can have negative side effects, such as joint pain and reduced sex drive.

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