Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.
Topical formulations, natural products, and CAM therapies are being used to treat Androgenic alopecia to avoid sideeffects of Finasteride and Minoxidil. The review covers various low-risk, alternative treatment options.
User experienced hair thickening with pyri but also sideeffects like reduced sex drive. Stopping pyri and returning to CB restored sex drive, suggesting pyri may go systemic or be incorrectly formulated.
A peptide-based delivery system for finasteride shows promise in reducing systemicsideeffects while maintaining hair growth effectiveness. Combining this with other treatments like minoxidil and RU58841 could enhance results with lower systemic absorption.
Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about sideeffects.