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An essential vasodilator with some anti-androgenic effects, has excellent safety record
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a topical anti-androgen with less systemic involvement
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natural substance from Neem tree with medicinal and pesticidal properties
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Research
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research Topical Use of Minoxidil in Children and Systemic Side Effects
Minoxidil use in children may cause heart issues.
research Lack of Endocrine Systemic Side Effects After Topical Application of Spironolactone in Men
Topical spironolactone cream doesn't cause hormone-related side effects in the body.
research Effects of Local and Systemic Medications on Eye Health: Adverse Reactions
Medications can cause eye problems, so regular eye check-ups are important.
research Sequential High- And Low-Dose Systemic Corticosteroid Therapy For Severe Childhood Alopecia Areata
High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.
research Comparing Compliance, Side Effects, and Satisfaction in Oral and Topical Minoxidil
Oral minoxidil is easier to use and more satisfying for hair loss treatment but may cause more unwanted hair growth.
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5 / 1000+ resultscommunity A Systemic Review on Topical Marketed Formulations, Natural Products, and Oral Supplements to Prevent Androgenic Alopecia: A Review
Topical formulations, natural products, and CAM therapies are being used to treat Androgenic alopecia to avoid side effects of Finasteride and Minoxidil. The review covers various low-risk, alternative treatment options.
community My Ultimate Hair Regrowth Regimen: Minimizing Systemic Exposure While Maximizing Results
The regimen includes using a diluted 5.5% Minoxidil / 0.025% Finasteride solution daily, microneedling weekly, and ketoconazole shampoo twice a week to minimize systemic exposure while maximizing scalp DHT reduction. The goal is to achieve hair regrowth with minimal side effects.
community 20M: Side Effects from Oral Finasteride, Resume Topical or Wait for Dermatologist?
The user experienced significant hair growth with oral finasteride but stopped due to side effects. They are considering trying topical finasteride again while waiting for a dermatologist appointment.
community Is it sufficient to block scalp DHT topically, or is it also necessary to reduce serum DHT? (My Question is Elaborated Below)
Topical finasteride can be as effective as oral finasteride for hair regrowth with fewer systemic side effects, but precise dosing is essential. Combining oral dutasteride with topical finasteride is not recommended due to dutasteride's stronger inhibition.
community Opinion on the recent clascoterone breakthrough?
Clascoterone has shown promising results in increasing hair density without systemic side effects, potentially offering benefits similar to finasteride. There is skepticism due to the lack of published photos despite the market interest.