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      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Alfatradiol

      a synthetic estrogen used topically as an anti-androgen

      learn Spironolactone

      powerful topical and oral anti-androgen used mostly by women

      learn Fluridil

      a topical anti-androgen with less systemic involvement

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      community Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)

      in Progress Pictures  16 upvotes 3 weeks ago
      The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.

      community 5 months topical spiro + minox + micro

      in Progress Pictures  6 upvotes 1 year ago
      A 35-year-old male uses topical minoxidil, spironolactone, and microneedling for hair loss, with spironolactone prescribed based on a DNA test indicating poor response to finasteride and dutasteride. Despite concerns about the test's validity and spironolactone's side effects, he reports stable or improved hair condition and no low testosterone symptoms.

      community 2 months difference - Before and After

      in Progress Pictures  431 upvotes 10 months ago
      The user shared progress pictures showing hair improvement after using 1mg oral finasteride and topical minoxidil daily for three months. They experienced initial side effects but reported no issues after five weeks, and the conversation includes discussions on the effectiveness and side effects of these treatments.