learn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
Search
forLearn
3 / 3 resultslearn Procyanidin
bioflavonoid found in plants with antioxidant and hair stimulating properties
learn Overview
Research
5 / 1000+ results
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Stem Cell Factor/c-Kit Signaling in Normal and Androgenetic Alopecia Hair Follicles
SCF and c-Kit decrease in AGA hair follicles, possibly affecting hair pigmentation and growth.
research Age-Dependent Loss of the Stemness and Antimicrobial Defense Function of Dermal Fibroblasts Is Mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research Age-Related Loss of Innate Immune Antimicrobial Function of Dermal Fat Is Mediated by Transforming Growth Factor Beta
Targeting TGFβ can improve skin immunity in older people.
research All-Trans Retinoic Acid Modulates Proliferation And Apoptosis Of Secondary Hair Follicle–Dermal Papilla Cells In Cashmere Goats Via The TGF-β2/Smad2/3 Pathway
The study examines the impact of all-trans retinoic acid (ATRA) on secondary hair follicle–derived dermal papilla cells (SHF-DPCs) in cashmere goats, highlighting the TGF-β2/Smad2/3 signaling pathway's role. ATRA was found to inhibit cell proliferation and promote apoptosis by inducing G1-phase cell cycle arrest and altering apoptosis-related proteins Bax and Bcl-2. Transcriptomic analysis identified 4,267 differentially expressed genes, with significant upregulation of TGF-β2. The effects were confirmed through rescue experiments using a TGF-β receptor inhibitor, which reversed ATRA-induced changes. These findings suggest ATRA modulates SHF-DPC behavior via the TGF-β2/Smad2/3 pathway, contributing to hair follicle regression and apoptosis, and offer insights into potential interventions for hair follicle-related disorders.
Community Join
5 / 81 resultscommunity A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.
Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.
community 30-Min Dermatology Visit – Best Questions to Ask About Balding? ( 175$ )
The conversation discusses hair loss treatments, focusing on finasteride, minoxidil, and other options like PRP and ketoconazole. It highlights the importance of asking specific questions during a dermatology visit to determine the cause of hair loss and appropriate treatments.
community Why is Minoxidil not enough for hair loss? (No fin)
Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.
community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment
by
MagicBold
in Research
865 upvotes
1 year ago The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.
community ladies and gentlmen, vitamin E is your hair follicles second best friend
Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.