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GlossaryThalidomide

medication causing birth defects, now used for specific conditions

Thalidomide is a medication that was originally developed in the late 1950s as a sedative and treatment for morning sickness in pregnant women. However, it was later found to cause severe birth defects, leading to its withdrawal from the market. Today, thalidomide is used under strict regulations to treat certain conditions like multiple myeloma and complications of leprosy, due to its anti-inflammatory and immunomodulatory properties.

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Research

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research Clinical and immunologic parameters during thalidomide treatment of lupus erythematosus

64 citations , May 2000 in “International Journal of Dermatology”

Thalidomide improved lupus symptoms but caused nerve damage in some patients.

research Lichen planopilaris treated with thalidomide

37 citations , December 2001 in “Journal of the American Academy of Dermatology”

Thalidomide significantly improved hair regrowth in a woman with lichen planopilaris.

research Selective Sensing of Darolutamide and Thalidomide in Pharmaceutical Preparations and in Spiked Biofluids

2 citations , November 2022 in “Biosensors”

A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.