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GlossaryTissue Damage

harm to body's tissues affecting function and structure

Tissue damage refers to harm or injury inflicted on the body's tissues, which can include skin, muscles, nerves, and internal organs. This damage can result from various causes such as physical trauma, infections, chemical exposure, or autoimmune reactions. In the context of hair and alopecia, tissue damage to the scalp can disrupt hair follicles, potentially leading to hair loss.

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Research

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research Author response: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

November 2021

Different types of skin cells and immune cells play a role in healing UV-damaged skin, with chronic UV exposure causing lasting damage to certain skin cells.

research The Effects of Multiple Power Densities of Carbon Dioxide Laser on Photothermal Damage in Rat Skin Tissue

May 2023 in “Current Applied Science and Technology”

Higher power CO2 laser causes more severe skin burns and damage.

Cell and Tissue Damage After Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects After Single and Fractional Doses

research Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses

14 citations , January 2014 in “Cells Tissues Organs”

Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.

research Mdm2-p53 Signaling in Tissue Homeostasis and the DNA Damage Response: A Dissertation

January 2012

Mdm2 is crucial for controlling p53 to maintain healthy cells and prevent tumors.

research dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration

128 citations , August 2015 in “Cell Stem Cell”

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

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Community Join

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community Could microneedling for the next 5 years cause any permanent damage?

in Microneedling 22 upvotes 2 years ago

Microneedling for hair loss and its potential long-term effects. Some users believe it can cause fibrosis and scar tissue if done too frequently or deeply, while others claim it has improved their hair loss when done correctly. There is limited scientific research on the topic.

community Injured temple with derma rolling

in Microneedling 2 upvotes 1 year ago

OP injured their temple using derma rolling and tretinoin, causing peeling and potential hair follicle damage. Users suggest the injury might be permanent, possibly resulting in scar tissue where hair won't grow.

community I need some guidance...

in Research/Science 6 years ago

A user experienced hair thinning due to traction alopecia from using Murray's Beeswax and is considering treatments like minoxidil and finasteride to reverse the damage. Another user suggests consulting a hair specialist, as the hair may not regrow if scar tissue has formed.

community Does microneedling damage scalp?

in Research/Science 12 upvotes 2 years ago

Microneedling does not prevent future hair transplants, but some surgeons report the skin becomes "harder" in treated areas. There is no clear evidence to confirm this effect.

community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

in Research/Science 66 upvotes 9 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

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Learn

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learn Epidermal Growth Factor

learn Stem Cell Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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Clinics

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12
Hair Loss Treatments
Labwest Hair Tissue AnalysisPerth, WA · AU

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