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Anti-Basal Cell Carcinoma Efficacy of a Topical Hedgehog Inhibitor Without Adverse Effects in Gorlin Syndrome Patients in a Phase 2 Randomized Controlled Trial

research 139 Anti-BCC efficacy of a topical hedgehog inhibitor without adverse effects in BCNS patients in a phase 2 randomized controlled trial

1 citations , April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

research Tofacitinib 2% ointment, a topical Janus kinase inhibitor, for the treatment of alopecia areata: A pilot study of 10 patients

48 citations , November 2017 in “Journal of the American Academy of Dermatology”

Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.

Discovery of 7-Methoxy-6-[4-(4-Methyl-1,3-Thiazol-2-yl)-1H-Imidazol-5-yl]-1,3-Benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

research Discovery of 7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]-1,3-benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a Topical Drug for Alopecia

6 citations , January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin”

A new compound shows promise as a topical treatment for hair loss.

research Randomized controlled trial to compare the efficacy of oral minoxidil 1.25 mg versus 2.5 mg versus topical 5% minoxidil in androgenetic alopecia

January 2026 in “Dermatologica Sinica”

Both oral and topical minoxidil effectively regrow hair in men with similar results.

research Topical and nutricosmetic products for healthy hair and dermal antiaging using “dual‐acting” (2 for 1) plant‐based peptides, hormones, and cannabinoids

13 citations , May 2021 in “FASEB bioAdvances”

Plant-based products can improve hair and skin health without harmful side effects.

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Community Join

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community Topical Spironolactone 2.5% MONOTHERAPY x 1 year (MALE)- Nothing else

in Progress Pictures 10 upvotes 2 years ago

A male in his early 40s, who experienced side effects from finasteride, used 2.5% topical spironolactone for one year with no side effects but minimal regrowth. He plans to try a 5% spironolactone solution next.

community 2.5 years on topical finasteride (0.1% fin + 7% min): hair success and why I stopped

in Finasteride/Dutasteride 17 upvotes 6 months ago

Topical finasteride with minoxidil effectively stabilized and thickened hair but caused side effects like brain fog, reduced libido, and emotional flattening, leading to discontinuation. The user switched to a new regimen including minoxidil, KX-826, and other treatments, noting improvements in libido and vivid dreams after stopping finasteride.

community Topical fin (0.1%) and min (5%) for almost 2 years

in Progress Pictures 11 upvotes 2 months ago

A 25-year-old male has been using topical finasteride (0.1%) and minoxidil (5%) for almost two years with no visible improvement but stable hair loss. Suggestions include switching to oral finasteride and minoxidil, considering stronger treatments like dutasteride, and consulting a doctor for personalized advice.

community topical min 2 years, topical fin 1 year

in Progress Pictures 8 upvotes 3 months ago

The user shared progress pictures showing improved hair density after using topical Minoxidil for two years and topical Finasteride for one year, with occasional microneedling. They adjusted Finasteride concentration over time and are considering additional treatments like a hair transplant.

community Used topical fin for 2 years, can i add oral fin too? (18 Male)

in Finasteride/Dutasteride 4 upvotes 2 months ago

An 18-year-old male using topical finasteride and minoxidil for hair loss is considering adding oral finasteride. Users advise against combining both forms of finasteride due to increased side effects and suggest switching to oral finasteride or dutasteride for better results, noting that finasteride is less effective on hairlines.

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