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research In-vivo uptake and metabolism of testosterone by the skin and other tissues of the rat

8 citations , May 1982 in “Journal of Endocrinology/Journal of endocrinology”

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

research Effects of mitotane treatment on human steroid metabolism: implications for patient management

26 citations , July 2012 in “Endocrine Connections”

Mitotane changes steroid breakdown, affecting cortisol availability.

research Quantitative analysis of 34 sex (pro)hormones, conjugates and bioactive oxidation products thereof in human plasma by GC- and LC-MS/MS and systematic investigation of overestimations of analyte concentrations not accounted for by method validation

4 citations , May 2024 in “Steroids”

The method accurately measures sex hormones in human plasma but can have small errors.

research Roles of steroid sulfatase in brain and other tissues

22 citations , January 2008 in “Physiological Research”

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

research Serum C-19 steroid sulphates in females with clinical hyperandrogenism

4 citations , January 1989 in “Journal of Steroid Biochemistry”

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

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community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community How uninformed the general public is about hair loss

in Chat 319 upvotes 2 years ago

The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.

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