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GlossaryVaginal Dryness

reduced lubrication in vaginal tissues causing discomfort and pain

Vaginal dryness refers to a condition where the vaginal tissues are not adequately lubricated, often leading to discomfort, itching, and pain during intercourse. This can be caused by hormonal changes, particularly a decrease in estrogen levels during menopause, but can also result from certain medications, stress, or underlying health conditions. It is sometimes referred to as vaginal atrophy or atrophic vaginitis when it involves thinning and inflammation of the vaginal walls.

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Research

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research A Phase II Study of Vaginal Testosterone Cream (TEST) vs. Estring for Vaginal Dryness or Decreased Libido in Women with Early Stage Breast Cancer (BC) Treated with Aromatase Inhibitors (AIs).

9 citations , December 2009 in “Cancer Research”

Both vaginal testosterone cream and Estring effectively manage vaginal dryness in women with early-stage breast cancer on aromatase inhibitors.

research Intravaginal Testosterone Improves Sexual Satisfaction and Vaginal Symptoms Associated With Aromatase Inhibitors

37 citations , September 2018 in “The Journal of Clinical Endocrinology and Metabolism”

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

research Histological and Gene Expression Analysis of the Effects of Menopause Status and Hormone Therapy on the Vaginal Introitus and Labia Majora

7 citations , January 2019 in “Journal of clinical medicine research”

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

research Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population

5 citations , September 2024 in “Maturitas”

The treatment effectively reduces menopausal symptoms and is well tolerated.

research Treatment of female sexual dysfunction in postmenopausal women—What is the evidence?

2 citations , March 2004 in “Reviews in Gynaecological Practice”

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

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community Started OM and Fin one year ago

in Female 5 upvotes 2 months ago

The user is experiencing significant hair shedding despite using 1.25mg oral minoxidil and 1mg finasteride daily for a year. They are advised to monitor health factors like vitamin levels and heart health, and consider increasing ferritin levels for optimal hair growth.

community Attempting to assist people with gyno sides on finasteride

in Research/Science 24 upvotes 1 year ago

Finasteride can cause gynecomastia due to hormonal imbalances. Management includes consulting an endocrinologist and using aromatase inhibitors like anastrozole or supplements like DIM and zinc.

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