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GlossaryVitamin D Receptor

protein that binds vitamin D to regulate gene expression

The Vitamin D Receptor (VDR) is a protein found in various cells throughout the body that binds to vitamin D, allowing it to regulate the expression of specific genes. This receptor plays a crucial role in maintaining calcium and phosphate balance, which is essential for healthy bone formation, and it also influences immune system function and hair follicle cycling.

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Research

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Stress-Induced c-Jun-Dependent Vitamin D Receptor Activation Dissects the Non-Classical VDR Pathway from the Classical VDR Activity

research Stress-induced c-Jun-dependent Vitamin D Receptor (VDR) Activation Dissects the Non-classical VDR Pathway from the Classical VDR Activity

31 citations , January 2007 in “Journal of biological chemistry/The Journal of biological chemistry”

Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

research Modulation of Vitamin D Receptor Activity by the Corepressor Hairless: Differential Effects of Hairless Isoforms

18 citations , October 2009 in “Endocrinology”

Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.

research Interactions of the Vitamin D Receptor with the Corepressor Hairless

42 citations , July 2007 in “Journal of Biological Chemistry”

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

Differential Activity of 2-Methylene-19-Nor Vitamin D Analogs on Growth Factor Gene Expression in Rhino Mouse Skin and Comparison to All-Trans Retinoic Acid

research Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid

2 citations , November 2017 in “PloS one”

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

research 975 Antifibrogenic activities of novel vitamin D3 analogs are dependent on VDR expression in human fibroblasts

April 2019 in “Journal of Investigative Dermatology”

New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.

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Community Join

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 100 upvotes 6 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Is Vitamin D the cause of my baldness or slow regrowth?

in Is this regrowth? 1 upvotes 9 months ago

The conversation discusses hair loss treatments, including oral finasteride, topical minoxidil, and microneedling, and the potential impact of Vitamin D and folic acid deficiencies on hair regrowth. It suggests that while male pattern baldness is the primary cause, addressing vitamin deficiencies may aid in improving regrowth.

community Almost 3 months | Topical Min (5%), 1 mg Fin, Microneedling, Biotin + Vitamin D Supplement

in Progress Pictures 601 upvotes 2 years ago

The conversation discusses a successful hair regrowth treatment involving topical Minoxidil (5%), 1 mg Finasteride, Microneedling, and Biotin + Vitamin D supplements. The user shares their routine and receives positive feedback on the significant progress made in just three months.

community Theoretically won't this be better than finasteride? Azelaic acid + zinc

in Research/Science 8 upvotes 3 years ago

The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 3 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

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Learn

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learn Overview

learn Vitamin D

vitamin you should probably be taking for general health might also help your hair a little

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Calcium D oantothenate

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