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research Mice with a null mutation of the TGFα gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation

578 citations , April 1993 in “Cell”

TGFα gene mutation in mice causes abnormal skin, wavy hair, curly whiskers, and sometimes eye inflammation.

research Curly : a new hair defect mutation in the SELH/bc mouse strain

January 2009

The curly mutation in SELH/Bc mice affects hair and may help study human genetic disorders.

research Developmental timing of hair follicle and dorsal skin innervation in mice

86 citations , May 2002 in “Journal of comparative neurology”

Nerve growth in mouse skin and hair follicles happens in stages and is closely linked to hair development.

research Icariin promotes mouse hair follicle growth by increasing insulin-like growth factor 1 expression in dermal papillary cells

22 citations , February 2017 in “Clinical and Experimental Dermatology”

Icariin helps mouse hair grow by boosting a growth factor in skin cells.

research The chemokine SDF-1/CXCL12 regulates the migration of melanocyte progenitors in mouse hair follicles

57 citations , April 2009 in “Differentiation”

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

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Community Join

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community My Hairline journey. The first photo taken is the day I took the pill. No date specific just know I’ve been on finasteride 22 months. 2 years November 14th. ASK ANYTHING. Oh yeah started minoxidil a year later. Once every day or every other day super inconsistent and never really use 1ml, maybe half

in Progress Pictures 326 upvotes 3 years ago

. Fin from Inhouse This user has been taking finasteride for 22 months and minoxidil for 1 year to reduce hair loss, with apparent success; they have also avoided tight cornrow hairstyles to further protect their hairline.

community 4 years of dutasteride monotherapy

in Progress Pictures 191 upvotes 3 years ago

The conclusion of the conversation is that the user experienced noticeable regrowth of hair after using dutasteride as a single treatment for about 1.5 years. No before photos were available.

community Finasteride - impact on Neurosteroids, which yes, \are important and not a garbage hormone

in Research/Science 163 upvotes 1 year ago

Finasteride may affect neurosteroids, impacting mood and sexual function, with varied user experiences. Some report side effects like depression and sexual dysfunction, while others find it effective for hair retention or prefer alternatives like Dutasteride or topical treatments.

community Seeking Advice on Norwood 3 Hairline at Age 15

in Basic Questions 533 upvotes 9 months ago

A 15-year-old is concerned about hair loss, possibly at Norwood 2 or 3, and is using shampoos and conditioners recommended by a trichologist. Suggestions include considering topical minoxidil and consulting a doctor about topical anti-DHT treatments like finasteride or RU58841, but avoiding 5-alpha-reductase inhibitors at this age.

community Topical Minoxidil is a pain in the ass for diffuse thinners

in Minoxidil 95 upvotes 3 years ago

Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

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