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GlossaryWnt3a

protein crucial for hair follicle development and regeneration

Wnt3a is a protein that plays a crucial role in cell signaling pathways, particularly in the regulation of cell growth, development, and differentiation. In the context of hair biology, Wnt3a is important for hair follicle development and regeneration, as it helps activate the pathways that promote hair growth and prevent hair loss.

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Research

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research Wnt Signaling in Skin Development, Homeostasis, and Disease

260 citations , December 2012 in “Cold Spring Harbor Perspectives in Biology”

Wnt signaling is crucial for skin development and health, and its disruption can cause skin diseases.

research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration

260 citations , June 2011 in “Cell”

Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

research The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

127 citations , January 2008 in “PloS one”

Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.

research Concise Review: Wnt Signaling Pathways in Skin Development and Epidermal Stem Cells

105 citations , October 2017 in “Stem cells”

Wnt signaling is crucial for skin development and hair growth.

research Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration

94 citations , June 2016 in “The FASEB Journal”

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

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