Alopecia Induced by Poly-L-Lactic Acid Injection

This case report describes a rare occurrence of alopecia in a 35-year-old woman following a poly-L-lactic acid (PLLA) injection, resulting in nonscarring alopecia with erythema and edema along the frontal hairline. The alopecia is attributed to extravascular compression and intravascular PLLA embolism, causing tissue ischemia. Diagnosis was confirmed through trichoscopy and histopathologic analysis, which showed lymphocytic inflammatory infiltrate and PLLA deposits forming foreign body granulomas. The report underscores the importance of early detection and management of this adverse event and highlights the need for dermatologists to be aware of the potential risks of PLLA injections.