Apoptotic Cell Death in Canine Hair Follicle

The study investigated the role of apoptotic cell death in canine hair follicles, aiming to understand its relationship with the hair cycle in dogs. Apoptosis, a process marked by DNA fragmentation, was previously linked to hair follicle growth and regression in various species. Using TUNEL assays and histological methods, the study found that apoptotic cells were present in both growing and regressing follicle epithelium in dogs, displaying characteristic morphological features. This suggested that apoptosis played a significant role in the hair cycle of dogs, similar to other species.