Chirality Effect on Physical and Biological Properties of Peptide-Based Hydrogels

This review examines the impact of chirality on the formation and properties of peptide-based hydrogels. It explores systems composed of peptides with all L- or D-amino acids, those with alternating chirality, and mixtures of L- and D-peptides. The study highlights the structural and mechanical differences between hydrogels formed by homochiral and heterochiral peptides. Additionally, it discusses the potential biological applications of these hydrogels, emphasizing the variations in properties based on chirality.