Chirality Effect on Physical and Biological Properties of Peptide-Based Hydrogels

This review examines how chirality affects the formation and properties of peptide-based hydrogels. It explores systems with peptides of all L- or D-amino acids, alternating chirality, and mixtures of L- and D-peptides. The review discusses the structural and mechanical differences between hydrogels formed by homochiral and heterochiral peptides and highlights their potential biological applications, emphasizing the distinctions between hydrogels with opposite or mixed chirality.