Effect of Carbon Dioxide Laser (10600nm) on Hydroxyproline in Mouse Skin

    May 2019 in “ Pakistan Journal of Pharmaceutical Sciences ”
    TLDR CO2 laser treatment may be more effective for skin rejuvenation.
    The study investigated the effects of 10600nm CO2 dot laser and Nd: YAG laser on skin aging in mice, focusing on the expression of MMP-1 and TIMP-1 proteins. It involved 45 female Wistar rats divided into 9 groups, with different treatments applied to their back skin. The CO2 laser showed a higher positive expression of MMP-1 and TIMP-1 compared to the Nd: YAG laser, with significant differences observed at 2 weeks post-irradiation. The study concluded that CO2 laser treatment had a more pronounced effect on these proteins, suggesting its potential efficacy in skin rejuvenation.
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