Taming of COVID-19: Potential and Emerging Application of Mesenchymal Stem Cells

The document reviewed the potential application of mesenchymal stem cells (MSCs) in treating COVID-19, focusing on their immunomodulatory and regenerative properties. MSCs were considered promising for reducing mortality and morbidity by modulating immune responses, preventing cytokine storms, and aiding tissue repair. Various studies and clinical trials, involving participant numbers ranging from 5 to 200, were conducted across multiple countries to assess the safety and efficacy of MSCs derived from sources like umbilical cords and adipose tissue. Preliminary results indicated that MSC therapy was safe and showed potential in improving oxygenation, reducing inflammation, and enhancing recovery in COVID-19 patients. However, limitations such as small sample sizes and lack of randomization were noted, highlighting the need for further research to confirm these findings and establish standardized treatment protocols.