Cutaneous Toxicities of MEK Inhibitor Use in Children: A Comparison of Binimetinib and Selumetinib

November 2024 in “ Pediatric Dermatology ”

Carli D. Needle, Lu Yin, Trevor K. Young, Steven G. Friedman, Soutrik Mandal, Devorah Segal, Kaleb Yohay, Nikita Lakdawala, Vikash S. Oza

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research IL-36γ Drives Skin Toxicity Induced by EGFR/MEK Inhibition and Commensal Cutibacterium Acnes

32 citations , December 2019 in “The Journal of clinical investigation/The journal of clinical investigation”

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

research Cutaneous Reactions to Targeted Therapies in Children with CNS Tumors: A Cross-Sectional Study

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Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.

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research Cutaneous Toxicities of MEK Inhibitor Use in Children: A Comparison of Binimetinib and Selumetinib

3 citations , November 2024 in “Pediatric Dermatology”