Dermatological Aspects of Gender Affirming Medical Treatment in Transgender and Gender Diverse People: A Systematic Review

    Jon Arcelus, Kamilla Kamaruddin, Walter Pierre Bouman
    TLDR Transgender individuals may face specific skin issues during gender-affirming treatments, needing personalized care.
    The systematic review investigates the dermatological effects of gender-affirming medical treatment (GAMT) in transgender and gender diverse (TGD) individuals, identifying common issues such as acne, androgenic alopecia, xerosis, and scarring. It highlights that trans men on testosterone therapy are more prone to acne and androgenetic alopecia, while feminizing hormone treatments can improve acne but may cause xerosis and melasma. The review stresses the importance of tailored dermatological care for TGD individuals, noting barriers like cost and lack of specific care. It recommends patient-specific prevention strategies and treatments, similar to those for cisgender patients, with considerations for hormonal therapies. Additionally, it underscores the need for careful management of surgical scars and hair removal before surgeries. Overall, the review calls for comprehensive dermatological care to enhance the quality of life and mental health of TGD patients.
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