TLDR Trichoscopy is a helpful tool for diagnosing Netherton syndrome.
Netherton syndrome (NS) is a rare genetic skin disorder characterized by congenital ichthyosiform erythroderma, trichorrhexis invaginata (TI), and atopic diathesis, with an incidence of 1 in 100,000–200,000 live births. This case report discusses a 6-year-old boy with NS, presenting with generalized scaly lesions and severe itching, initially misdiagnosed as atopic dermatitis. Trichoscopy revealed characteristic bamboo, golf tee, and matchstick hair patterns, aiding in the diagnosis. NS is challenging to diagnose due to overlapping symptoms with other conditions, but trichoscopy serves as a valuable non-invasive diagnostic tool. Although there is no complete cure, treatment options include topical corticosteroids and antihistamines. Regular follow-up is essential due to the risk of skin cancer.
66 citations
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June 2018 in “British Journal of Dermatology” European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.
30 citations
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February 2015 in “Anais Brasileiros de Dermatologia” Trichoscopy is useful for diagnosing Netherton syndrome in children with skin issues.
41 citations
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December 2008 in “Pediatric Dermatology” Trichoscopy can diagnose Netherton syndrome without pulling hairs.
33 citations
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March 2006 in “Seminars in cutaneous medicine and surgery” The document explains how to identify different hair problems using a microscope.
January 2025 in “Clinical Dermatology Review” Trichoscopy helps accurately diagnose Netherton syndrome, often mistaken for atopic dermatitis.
59 citations
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June 2008 in “Journal of The American Academy of Dermatology” The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
36 citations
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August 2018 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.
November 2019 in “Harper's Textbook of Pediatric Dermatology” Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
