Discoid Lupus Erythematosus Successfully Treated With Deucravacitinib

    April 2024 in “ JAAD Case Reports ”
    Nnenna Ezeh, Ruth Ann Vleugels, Neda Shahriari
    TLDR Deucravacitinib may effectively treat discoid lupus erythematosus.
    A 65-year-old woman with discoid lupus erythematosus (DLE) and palmoplantar pustular psoriasis was successfully treated with deucravacitinib, a selective TYK-2 inhibitor, experiencing rapid improvement in DLE symptoms within 1 month. This case indicates that deucravacitinib could be a promising treatment for DLE, potentially reducing the need for multiple medications. Further research is needed to assess the broader efficacy of TYK-2 inhibitors for DLE and other related conditions.
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