Comparative Effectiveness of Regenerative Biologics in Aesthetic Dermatology: A Systematic Review with Quantitative Synthesis Evaluating Exosomes, PRP, and Stem-Cell-Derived Therapies on Skin and Hair

    January 2026 in “ Zenodo (CERN European Organization for Nuclear Research) ”
    Alaa Abdelfattah,Agha Syed Zain Haider,Abdulrahman Ahmed Mubarak Bensumaidea,Yusur Al-Sudani,Zain Husam Haddad,Seleen Kazzaz,Vareen Kazzaz,Mehreen Nawaz Khan,Shirin Alansari,Kiran khan,Saad Ali Khan
    Image of study
    TLDR Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
    The systematic review evaluates the comparative effectiveness of regenerative biologics, specifically exosomes, platelet-rich plasma (PRP), and stem-cell-derived therapies, in aesthetic dermatology focusing on skin and hair. The study synthesizes quantitative data to assess the impact of these therapies on hair growth and skin rejuvenation. The findings suggest that all three therapies show promise in improving hair density and skin quality, with exosomes and stem-cell-derived treatments demonstrating slightly superior outcomes compared to PRP. However, the review highlights the need for more extensive clinical trials to establish definitive conclusions, as current studies vary in methodology and sample size.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 204 results

      community Stem cells for hair, does it work?

      in Technology  7 upvotes 3 months ago
      Stem cell treatments for hair restoration can be effective, but results vary and depend on factors like the type of stem cells used and timing of treatment. PRP and exosomes have shown some success, while costs and effectiveness differ by location, with South Korea and Turkey offering more affordable options.

      community STEM CELL TREATMENT FOR HAIR LOSS at home

      in Treatment  6 upvotes 5 years ago
      User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.

      community Seeking Advice: Stem Cell Therapy vs. PRP for Hair Loss

      in Treatment  2 upvotes 1 year ago
      The conversation is about someone seeking advice on choosing between stem cell therapy and PRP for treating hair loss, asking for personal results, side effects, overall satisfaction, and recommendations from others.

      community After Exosomes Treatment.

       15 upvotes 6 years ago
      A user who underwent exosomes treatment for hair loss and reported their experience, with other users discussing the procedure and offering advice. They discussed options such as finasteride, minoxidil, RU58841 and hair transplants.

    Similar Research

    5 / 1000+ results