Comparative Effectiveness of Regenerative Biologics in Aesthetic Dermatology: A Systematic Review with Quantitative Synthesis Evaluating Exosomes, PRP, and Stem-Cell-Derived Therapies on Skin and Hair
January 2026
in “
Zenodo (CERN European Organization for Nuclear Research)
”
TLDR Exosomes and stem-cell therapies slightly outperform PRP in improving hair and skin, but more research is needed.
The systematic review evaluates the comparative effectiveness of regenerative biologics, specifically exosomes, platelet-rich plasma (PRP), and stem-cell-derived therapies, in aesthetic dermatology focusing on skin and hair. The study synthesizes quantitative data to assess the impact of these therapies on hair growth and skin rejuvenation. The findings suggest that all three therapies show promise in improving hair density and skin quality, with exosomes and stem-cell-derived treatments demonstrating slightly superior outcomes compared to PRP. However, the review highlights the need for more extensive clinical trials to establish definitive conclusions, as current studies vary in methodology and sample size.
