Endocrinologic Diagnosis in Hirsutism and Androgenetic Alopecia in Women

    December 1990 in “ PubMed ”
    J. Pichl, Hermann Schell
    TLDR Hirsutism and androgenetic alopecia in women are often due to increased androgen effects, and antiandrogen treatment is recommended to prevent further issues.
    The document discussed the endocrinologic diagnosis of hirsutism and androgenetic alopecia in women, attributing these conditions to an enhanced effect of androgens on hair follicles. This could result from increased bio-available androgens or heightened sensitivity of target organs. It noted that there were no definite correlations between circulating androgens and their biological effects. Despite most cases of hyperandrogenemia not being severe, treatment with antiandrogens was recommended to prevent further metabolic and fertility issues. Additionally, hirsutism could indicate steroid biosynthesis defects or Cushing's syndrome. In cases of severe hyperandrogenemia, with testosterone levels exceeding 2 ng/ml and DHEA-S levels over 8000 ng/ml, ovarian or adrenal gland tumors should be ruled out.
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