Folliculitis decalvans managed with adalimumab: A case report

    December 2023 in “ Clinical Case Reports ”
    Adel Alsantali, Razan Baghdadi, Yara Alghamdi, Elham Bin Abbas, Rafah Ghazi
    TLDR Adalimumab effectively stabilized severe folliculitis decalvans, preventing further hair loss and inflammation.
    This case report discusses the management of a 40-year-old female with recalcitrant folliculitis decalvans (FD), a challenging inflammatory scalp condition, using Adalimumab. The patient, who had a history of psoriasis vulgaris, presented with significant hair loss and scalp inflammation. Initial treatments with antibiotics and topical solutions were insufficient. Adalimumab, an anti-TNF-α monoclonal antibody, was administered following the hidradenitis suppurativa protocol, leading to stabilization of the condition and no new scarring after 10 months. The report highlights the potential of Adalimumab as an effective off-label treatment for severe FD, advocating for its use to preserve hair follicles and prevent further inflammation.
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