TLDR High-dose steroid pulse therapy effectively regrows hair in severe multifocal alopecia areata.
The study evaluated the efficacy of high-dose steroid pulse therapy in 17 Taiwanese patients with severe alopecia areata (AA) affecting more than 40% of the scalp. Patients were treated monthly for six sessions, with children receiving oral prednisolone and adults receiving intravenous methylprednisolone. The results showed that 64.7% of patients experienced more than 75% hair regrowth, particularly those with multifocal AA. Relapses occurred in some cases, and the response varied with the type of AA. No major side effects were observed, indicating that the therapy was effective and well-tolerated for severe multifocal AA lasting less than 2 years.
November 2020 in “Journal of The American Academy of Dermatology” Oral JAK inhibitors help regrow hair in alopecia patients.
March 2020 in “QJM: An International Journal of Medicine” Standard intralesional corticosteroids are the best treatment for patchy alopecia areata.
Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.
71 citations
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March 2009 in “Seminars in cutaneous medicine and surgery” Alopecia areata can cause unpredictable hair loss, and treatments like corticosteroids and minoxidil may help but have varying side effects.
21 citations
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March 2002 in “PubMed” High-dose steroid pulse therapy effectively regrows hair in severe multifocal alopecia areata.
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February 1996 in “International Journal of Dermatology” A 300 mg monthly pulse of prednisolone effectively and safely treats widespread alopecia areata.
