Hyperandrogenism in Dermatology: Pathogenesis, Diagnosis, and Therapeutic Strategies

April 2026 in “ Russian Journal of Skin and Venereal Diseases ”

Alina Zybareva, Yuri Perlamutrov, Dina Klyuchnikova

hyperandrogenism androgenetic alopecia acne hirsutism androgens dermatology female pattern hair loss male hormones

TLDR Hyperandrogenism in women affects skin and quality of life, but treatment is complex due to lack of guidelines.

This review highlights the complexity of hyperandrogenism in women, focusing on its dermatological manifestations such as androgenetic alopecia, acne, and hirsutism, which significantly impact quality of life. The condition is linked to elevated androgen levels and can lead to reproductive and psychoemotional issues. Despite its prevalence, there are no specific treatment guidelines, complicating standardized care. The review emphasizes the need for a personalized, interdisciplinary approach to effectively diagnose and treat hyperandrogenism, drawing on recent studies and publications from major medical databases.

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