Hyperandrogenism in Dermatology: Pathogenesis, Diagnosis, and Therapeutic Strategies

April 2026 in “ Russian Journal of Skin and Venereal Diseases ”

Alina Zybareva, Yuri Perlamutrov, Dina Klyuchnikova

hyperandrogenism androgenetic alopecia acne hirsutism androgens dermatology female pattern hair loss male hormones

TLDR Hyperandrogenism in women affects skin and quality of life, but treatment is complex due to lack of guidelines.

This review highlights the significance of hyperandrogenic conditions in women, which are linked to skin changes like androgenetic alopecia, acne, and hirsutism, impacting quality of life and potentially causing reproductive and psychoemotional issues. The review emphasizes the complexity of treating hyperandrogenism due to the lack of dedicated medical guidelines, complicating standardized treatment approaches. It systematically compiles current knowledge on the pathogenesis, clinical manifestations, diagnosis, and treatment of these conditions, offering a comprehensive overview for modern dermatology.

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