Understanding the Impact of the Skin Microbiome on Dermatological Assessments and Therapeutic Innovation

The review highlights the significant role of the skin microbiome in dermatological health, particularly in conditions like acne, aging, hyperpigmentation, and hair disorders. Dysbiosis, or microbial imbalance, is linked to inflammation and skin barrier dysfunction, exacerbating these conditions. Specific microbial profiles, such as Cutibacterium acnes with acne and Corynebacterium with aging, are discussed. The gut-skin axis and its influence on skin health are also explored. Innovative therapeutic strategies, including prebiotics, probiotics, and postbiotics, are emphasized for their potential to enhance skin health and treatment outcomes. The review underscores the importance of microbiome-informed approaches in personalized dermatology and suggests future research should focus on standardizing microbiome studies and exploring postbiotics as stable, effective agents in skincare.