Keratolysis in a Patient with Pemphigus Vulgaris

    October 2001 in “ British Journal of Ophthalmology
    M. Suami
    TLDR Corneal issues in pemphigus vulgaris may require surgery if medication is not followed.
    The document described a case of a 41-year-old man with pemphigus vulgaris, an autoimmune blistering disease, who experienced severe keratolysis necessitating corneal transplantation. Despite being prescribed prednisolone and cyclosporine, the patient had an acute exacerbation due to non-compliance with corticosteroid therapy, leading to increased discharge and visual loss. His visual acuity remained 20/20 in both eyes, but intraocular pressure was elevated. This case highlighted the rare occurrence of corneal involvement in pemphigus vulgaris and the potential need for surgical intervention.
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