A Comparative Study Between Laparoscopic Sleeve Gastrectomy and One-Anastomosis Gastric Bypass on Serum Zinc Levels

December 2025 in “ Obesity Surgery ”

Ahmed Mohammed Salah Eldeen Othman Elansary, M. Fahmy, Saeed Bakry Elsayed, Mohamed Yacoub, Abdelrahman Mostafa Ibrahim Mohamed

serum zinc levels hair loss hypozincemia bariatric surgery

TLDR One-anastomosis gastric bypass leads to lower zinc levels and more symptoms than sleeve gastrectomy.

This study compared the effects of laparoscopic sleeve gastrectomy and one-anastomosis gastric bypass on serum zinc levels in 50 patients with severe obesity over one year. It found that patients who underwent one-anastomosis gastric bypass experienced a greater decline in serum zinc levels at 6 and 12 months postoperatively compared to those who had sleeve gastrectomy. The bypass group also showed a higher incidence of symptoms associated with low zinc levels, such as hair loss, diarrhea, and delayed wound healing. The findings suggest that one-anastomosis gastric bypass is linked to a higher risk of hypozincemia and related symptoms, highlighting the importance of routine zinc monitoring after bariatric surgery.

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A Comparative Study Between Laparoscopic Sleeve Gastrectomy and One-Anastomosis Gastric Bypass on Serum Zinc Levels

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