Microneedle Frequency Adjunct to 2% Minoxidil in Female Androgenetic Alopecia: A Randomized Controlled Trial

This study investigated the efficacy of combining microneedling with 2% topical minoxidil in treating female androgenetic alopecia (AGA) over 24 weeks. Involving 245 women, the trial compared minoxidil alone, minoxidil with monthly microneedling, and minoxidil with bi-weekly microneedling. Results showed significant increases in target area non-vellus hair count (TAHC) across all groups, but no significant differences between them. Secondary outcomes, such as hair shaft diameter and hair density, were also similar across groups. The study concluded that adding microneedling did not enhance the clinical benefits of minoxidil alone. Limitations included its single-center, open-label design and lack of patient-reported outcomes.