Microneedling-Assisted Panax Ginseng Exosome Protocol for Vulvovaginal Symptoms and Vulvar Skin Tone Changes: A Preliminary Pilot Observational Study

This preliminary pilot observational study involving 14 women explored the effects of a microneedling-assisted Panax ginseng exosome protocol on vulvovaginal symptoms and vulvar skin tone. Over a 6-week period, participants underwent three treatment sessions, resulting in significant improvements in patient-reported outcomes, including decreased scores on the Vulvovaginal Symptom Questionnaire and the Day-to-Day Impact of Vaginal Aging questionnaire. The study also noted qualitative improvements in skin tone and pigmentation, with transient pain reported post-procedure. No serious adverse events were observed. However, due to the study's small size and design limitations, these findings are considered preliminary and suggest the need for further research.