Microneedling for Androgenetic Alopecia: A Synergistic Strategy Enhancing Drug Delivery and Follicular Regeneration

Microneedling (MN) offers a promising approach for treating androgenetic alopecia (AGA) by enhancing drug delivery and promoting hair follicle regeneration. This review highlights MN's ability to improve the efficacy of topical treatments like minoxidil and its synergistic effects when combined with therapies such as platelet-rich plasma, finasteride, and dutasteride. Although preliminary studies indicate potential benefits, the evidence is limited by small sample sizes and short follow-up periods. Larger, well-designed trials are necessary to establish MN's clinical role. MN bridges the gap between topical treatments and surgical options, with classical MN and drug-loaded microneedle systems offering distinct mechanisms and applications.