Autonomous, Moisture-Driven Flexible Electrogenerative Dressing for Enhanced Wound Healing
February 2025
in “
Advanced Materials
”
TLDR The dressing speeds up wound healing by 41% using moisture-generated electricity and antibacterial properties.
This study presents an autonomous, moisture-driven flexible electrogenerative dressing (AMFED) that enhances chronic wound healing by integrating a moist-electric generator (MEG), antibacterial hydrogel dressing, and molybdenum electrodes. The MEG generates a stable direct current of 0.61 V from moisture, providing electrical stimulation and antibacterial activity against Staphylococcus aureus and Escherichia coli. The AMFED promotes macrophage polarization to the reparative M2 phenotype and regulates inflammatory cytokines. In vivo studies using a diabetic mouse model show that AMFED accelerates wound healing by approximately 41% compared to controls, promoting nerve regulation, epithelial migration, and vasculogenesis, offering a novel platform for wound treatment.
