Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing
December 2025
in “
Nano Letters
”
tannin-modified cellulose-polypyrrole nonwoven dressing TA/Cell@PPy tannic acid antimicrobial protection electrotherapy S. aureus E. coli conductive polypyrrole endogenous electric fields re-epithelialization granulation tissue collagen matrix organization angiogenesis biomimetic nanofibrous architecture biocompatibility secondary trauma infection control tissue regeneration antibacterial dressing conductive dressing wound healing dressing antimicrobial dressing electric field therapy bacterial infection control wound closure tissue repair
TLDR The new dressing speeds up wound healing by fighting bacteria and boosting natural electric fields.
The study presents a novel tannin-modified cellulose-polypyrrole nonwoven dressing (TA/Cell@PPy) designed to accelerate wound healing by combining antimicrobial protection with electrotherapy. The dressing utilizes tannic acid for antibacterial activity against S. aureus and E. coli, and conductive polypyrrole to enhance endogenous electric fields, promoting re-epithelialization. In vivo evaluations show that TA/Cell@PPy significantly speeds up wound closure through enhanced granulation tissue, optimized collagen matrix organization, and stimulated angiogenesis. Its biomimetic nanofibrous architecture ensures biocompatibility and prevents secondary trauma during dressing changes, offering a promising solution for complex wound management by addressing infection control and tissue regeneration simultaneously.
