TLDR The inner root sheath in hair follicles plays a key role in hair growth and health.
The review re-evaluates the role of the inner root sheath (IRS) in human hair follicles, traditionally seen as a structural component. It suggests that the IRS has broader functions, including involvement in signaling processes that affect folliculogenesis, anagen phase regulation, cell differentiation, immunomodulation, and keratinization. This positions the IRS as a dynamic and significant player in hair follicle biology, with important regulatory functions that have been previously underexplored.
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
10 citations
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June 2016 in “Wound Repair and Regeneration” The microenvironment, especially mechanical forces, plays a crucial role in hair growth and could lead to new treatments for hair loss.
2 citations
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January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
New hair regrowth therapies show promise but need more research.
5 citations
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February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
