Origanum Vulgare L. Leaf Extract Alleviates Finasteride-Induced Oxidative Stress in Mouse Liver and Kidney

The study concluded that Origanum vulgare L. leaf extract effectively alleviated oxidative stress in the liver and kidney of mice induced by finasteride. The extract, particularly at doses of 200 and 400 mg/kg/day, significantly improved liver and kidney function, reduced inflammatory cytokines, increased antioxidant status, and decreased oxidative stress markers. Histopathological analysis confirmed these protective effects, indicating that Origanum vulgare extract could be a beneficial supplement for reducing oxidative stress and mitigating finasteride-induced hepatic and renal damage.