Ovarian Function After Renal Transplantation: Comparison of Cyclosporin A With Azathioprine and Prednisone Combination Regimens

    August 1984 in “ BJOG An International Journal of Obstetrics & Gynaecology ”
    David J. Handelsman, I.F.W. McDowell, Ian D. Caterson, David J. Tiller, Bruce M. Hall, John R. Turtle
    TLDR Ovarian function was similar in both treatment groups, but both caused excessive hair growth.
    The study assessed ovarian function in 24 women after renal transplantation, comparing those treated with cyclosporin A (10 patients) to those treated with a combination of azathioprine and prednisone (14 patients). There were no differences in clinical or endocrine indices of ovarian function between the two groups. However, excessive hair growth was common in both groups. Higher levels of testosterone and dehydroepiandrosterone in cyclosporin-treated women were attributed to prednisone-induced suppression of adrenal androgen output in the azathioprine and prednisone group. The presence of excessive hair growth in postmenopausal women on both treatments suggested that hypertrichosis was a consequence of renal transplantation rather than a specific side effect of cyclosporin A.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 24 results

      community Making your own RT1640 in China

      in Research/Science 4 years ago
      RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

      community RT1640 - Gray Hair Reversal Recipe

      in Research/Science  3 upvotes 3 years ago
      The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

      community Forgotten 'Total Revival' Stack

      in Research/Science  42 upvotes 9 months ago
      Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.

      community Starting Way-316606 for the first time today.

      in Research/Science  30 upvotes 11 months ago
      A user is experimenting with a homemade solution of WAY-316606 for hair regrowth, combining it with other treatments like minoxidil and dutasteride. The community expresses concern over the safety and mental health implications of such drastic measures, with mixed opinions on the effectiveness of WAY-316606.

    Similar Research

    5 / 1000+ results
      Acne-Associated Syndromes

      research Acne-Associated Syndromes

      January 2019 in “Springer eBooks”
      Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.
      Acne and Its Management

      research Acne and Its Management

      7 citations , November 2013 in “Pediatrics in Review”
      Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.
      Obstetric Dermatology

      research Obstetric Dermatology

      January 2009 in “Springer eBooks”
      The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
      Acne

      research Acne

      4 citations , January 2019
      Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.