Phytochemical Profiling, Green Synthesis of Ag, Cu, Fe, and Zn Nanoparticles, and In Vitro Biological Activities of Delphinium Brunonianum Royle

    May 2026 in “ Scientific Reports
    Sajjad Azam, Amjad Hussain, Muhammad Sajid Hamid Akash, Khayala Mammadova, Saman Zahra, Muhammad Imran, Iftikhar Ali, Ismayil Gafarov, Abdur Rauf, Mohamed AbdElrahman, Nada H. Aljarba, Alaa Ismail, Katabathini Narasimharao, Shagufta Kamal
    TLDR Delphinium brunonianum shows promise for medical use due to its bioactive compounds and effective nanoparticle synthesis.
    The study on Delphinium brunonianum Royle highlights its diverse phytochemical profile and potential pharmacological applications. The research involved the green synthesis of Ag, Cu, Fe, and Zn nanoparticles and assessed their in vitro biological activities. Key findings include the ethyl acetate extract and Ag nanoparticles showing significant radical scavenging activity with 93.43% and 66.99% inhibition, respectively. The n-hexane extract demonstrated high acetylcholinesterase inhibition at 57.56%, while Cu and Fe nanoparticles showed notable lipase inhibition at 72.52% and 65.90%, respectively. Cu nanoparticles also exhibited a high tyrosinase inhibition of 78.18%. Antibacterial and antifungal activities were observed with a 21.66 mm zone of inhibition for n-hexane extract and 27.3 mm for Zn nanoparticles. These results suggest that D. brunonianum is a promising source of bioactive compounds and an effective medium for nanoparticle synthesis, with potential future applications in medical fields.
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