Phytoconstituent Based Formulations and Phenolic Compounds in Acne Management with A Comprehensive Review of Traditional Remedies, Modern Strategies, and Therapeutic Innovations

July 2026 in “ Current Pharmaceutical Analysis ”

Keren Celestina Mendonce, Naveen Palani, Aswin Krishnamurthy, Nandhini Sundaresan, Suriyaprakash Rajadesingu

Aloe vera Tea Tree Oil Neem herbal formulations anti-inflammatory properties antimicrobial properties acne management traditional botanicals phytoconstituents phenolic compounds Aloe Melaleuca oil Indian Lilac

TLDR Herbal remedies can help with acne but should be used with other treatments.

This review explores the use of herbal remedies in acne management, highlighting both traditional botanicals like Aloe vera, Tea Tree Oil, and Neem, and modern advancements in herbal formulations. It discusses the anti-inflammatory and antimicrobial properties of these remedies and examines scientific evidence supporting their efficacy. While herbal treatments show promise as adjunctive options, they should be used alongside established therapies due to limited large-scale clinical studies and variability in formulations. The review calls for further research to better understand the mechanisms and optimize the clinical use of herbal remedies in acne treatment.

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