Predicting Quality of Life from Symptom Experience and Symptom Management Behaviors in Women with Ovarian Cancer Receiving Chemotherapy: A Cross-Sectional Study
May 2026
in “
Pacific Rim International Journal of Nursing Research
”
TLDR Symptom interference negatively affects quality of life in women with ovarian cancer.
This study examined the impact of symptom experiences and management behaviors on the quality of life in 96 women with ovarian cancer undergoing chemotherapy in Thailand. The research found that while participants experienced multiple symptoms, numbness/tingling and fatigue were most common, with neuropathy and fatigue being the most severe. Symptom management was moderately effective, notably improving hair loss and nausea, but not neuropathy. Quality of life was generally rated as good, with symptom experiences significantly affecting it, though management effectiveness did not. Symptom interference was a significant negative predictor of quality of life, explaining 28.6% of its variance. The study highlights the importance of comprehensive symptom assessments and targeted interventions to reduce interference, neuropathy, and fatigue to enhance quality of life.